A sub-study of the POISE-3 randomized trial examined effects of a perioperative hypotension-avoidance strategy versus a hypertension-avoidance strategy on the risk of acute kidney injury.

Garg AX, Marcucci M, Cuerden MS, Sontrop JM, Painter TW, Lomivorotov V, Sessler DI, Chan MTV, Borges FK, Leslie K, Duceppe E, Parikh CR, Roshanov P, Martínez-Zapata MJ, Wang CY, Xavier D, Efremov S, Landoni G, Kleinlugtenbelt YV, Szczeklik W, Schmartz D, Meyhoff CS, Short TG, Amir M, Torres D, Wittmann M, Patel A, Ruetzler K, Parlow JL, Jayaram R, Polanczyk CA, Fleischmann E, Tandon V, Astrakov SV, Conen D, Kei Wu WK, Cheong CC, Ayad S, Kirov M, de Nadal M, Likhvantsev VV, Paniagua P, Aguado HJ, Ofori SN, Vincent J, Copland I, Balasubramanian K, Biccard BM, Srinathan S, Ismoilov S, Wang MK, Kurz A, Belley-Cote EP, Bhatt K, Eikelboom J, Gross P, Lamy A, McGillion M, McIntyre W, Richards T, Spence J, Van Helder T, Whitlock R, Devereaux P